Dextromethorphan. Or maybe you searched for ‘dexamethorphan’.

Looking at the amount of people that ended up on my blog reading about my shitty life because of ‘dexamethorphan‘, I have decided to make a real post on this … dexamethorphan/ dextromethorphan.

A DXM overdose can occur when DXM is taken at doses that are lethal or toxic and suppresses the central nervous system.

Alternative names for dextromethorphan OD includes: DXM overdose; Robo overdose; Orange crush overdose; Red devils overdose; Triple C’s overdose

I assume that you are already know shit like DXM is an antitussive and that you find it in cough syrup because this is precisely why you googled for dexamethorphan because you are planning on overdosing. Well, that’s what I’m assuming. Feel free to defend for yourself.

Dextromethorphan is classified as a semisynthetic morphine derivative that does not have analgesic properties and does not respond consistently to naloxone (Narcan) administration. High doses may cause it to react as a central nervous system depressant and a dissociative anesthetic (similar to ketamine). Toxic effects are primarily anticholinergic in nature and include altered sensorium (ranging from mild lethargy to unresponsiveness), hyperthermia, tachycardia, hypertension, dry mucous membranes, visual and auditory hallucinations, agitation, ataxia, aphasia and a variety of gastrointestinal symptoms including emesis, abdominal cramping and hematemesis. Large ingestions can cause seizures, respiratory depression and loss of airway reflexes.

It’s okay if you don’t understand the above part, ’cause you’re still gonna OD. But you saw those key words: visual and auditory hallucinations, agitation,  altered sensorium …

Basically, DXM works by decreasing activity in the part of the brain that causes coughing. But that’s probably not what you want it to do. It has euphoric dissociative effects, which means that when exceeding label-specified maximum dosages, DXM acts as a dissociative hallucinogen.

So … what’s the dosage that is too low and uncool for you who only want to get high? The recommended dosage for adults and children aged 12 years and older is 60-120 mg daily in divided doses.

Recreational use of DXM (that’s the nice way of saying DXM OD) is sometimes referred to in slang form as “robo-tripping”, whose prefix is derived from the Robitussin brand name of cough medicine, or “Triple Cs” which is derived from the Coricidin brand name of cough & cold medicine (since the pills were printed with CCC on them).

DXM’s hallucinogenic and dissociative effects can be attributed largely to dextrorphan (DXO), a metabolite produced when dextromethorphan metabolizes within the body. Both dextrorphan and dextromethorphan are NMDA receptor antagonists but dextrorphan is more potent than dextromethorphan in terms of overdosing.

DXM, when consumed in low “recreational doses” (between 100 & 200 mg), is described as having a euphoric effect. With middle doses (about 400 mg), intense euphoria, vivid imagination, and closed-eye hallucinations may occur. With high doses (600 mg), profound alterations in consciousness have been noted, and users often report out-of-body experiences or temporary psychosis. Flanging (speeding up or slowing down) of sensory input is also a characteristic effect of recreational use.

Apparently there’s this “The DXM FAQ” by William E. White, that classifies dextromethorphan’s high-dose effects into four or five plateaus. Note: The dosages are specified in ratios of milligrams (of the drug) per kilogram (of one’s body mass).

According to “The DXM FAQ”,

First plateau:

At a dosage of 1.5 to 2.5 mg/kg, effects include alertness, restlessness, increased heartbeat, increased body temperature, intensification of emotions, euphoria, loss of balance, and slight intoxication.

Second plateau:

At 2.5 to 7.5 mg/kg, effects are similar to the first plateau, but with heavier intoxication, choppy sensory input, a dreamlike state of consciousness, some detachment from outside world, and closed-eye hallucinations.

Third plateau:

At 7.5 to 15.0 mg/kg, effects include flanging of visual effects, difficulty recognizing people or objects, chaotic blindness, dreamlike vision, inability to comprehend language, abstract hallucinations, delayed reaction time, decision making impairment, feelings of peace and quiet, near complete loss of motor coordination, short-term memory impairment, and/or feelings of rebirth.

Fourth plateau:

At 15.0 mg/kg or more, an individual may experience a perceived loss of contact and control with their own body, changes in visual perception, out-of-body experiences, perceptions of contact with “superior” beings, other miscellaneous delusions, lack of movement or desire to move, rapid heart rate, complete blindness, increased hearing, and intensification of third plateau effects.
Plateau Sigma:

2.5-7.5 mg/kg every three hours for 9–12 hours; occurs by prolonging dosage. Plateau sigma is marked by the presence of psychosis with visual and auditory hallucinations. Users have reported that inclinations manifest as auditory hallucinations; rather than simply feeling tired and sitting down, a user might hear a voice saying, “sit down now, you’re tired,” and feel inclined to obey. White says that of all the reports of Plateau Sigma experiences he received, over half were described as unpleasant.

Some users report that DXM dosages are affected significantly by bodyweight and lighter users should start with lower dosages. Because everyone reacts differently, it is a better idea to start at lower dosages and slowly work up rather than jumping in at a higher dose. Some people are very sensitive to the effects and may be overwhelmed by dosages that are minimal for others.

Here are some symptoms of DXM OD, in case you’re not sure if you’re overdosing enough to be on OD yet, if that makes sense.

  • Nausea and vomiting
  • Constipation or diarrhea
  • Drowsiness
  • Lethargy
  • Dizziness
  • Disorientation
  • A rapid heartbeat (tachycardia)
  • Reduced consciousness, or stupor
  • Overexcitability
  • Loss of contact with reality (psychosis)
  • Lack of muscle coordination
  • Involuntary eye movements
  • Blurred vision
  • Uncontrolled and involuntary muscle movements or contractions
  • Seizures
  • Slow or irregular breathing
  • Signs of serotonin syndrome, such as:
  • Confusion
  • Seeing or hearing things that are not really there (hallucinations)
  • A fast heartbeat (tachycardia)
  • Increased blood pressure (hypertension)
  • Fever
  • Sweating
  • Shivering
  • Tremors
  • Muscle spasms
  • Overactive reflexes.

However, a few things to take note of:

  • Drinking alcohol can increase some of the side effects of dextromethorphan. (which are not necessarily the ones you like)
  • Taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) together with cough medicine can increase your risk of unpleasant side effects.
  • And if you take any MAO inhibitors, life-threatening side effects can occur if you take dextromethorphan before the MAO inhibitor has cleared from your body, and that is not very cool.
  • DXM products containing acetaminophen should not be used recreationally. High doses of acetaminophen can be fatal.
  • DXM, when taken up to 2,500-20,000mg, brings risks of death.

Antidote to dextromethorphan overdose is naloxone, administered intravenously. And if you ever get sent to an emergency room, these are some things that you may expect:

  • Activated charcoal
  • Breathing support (oxygen and possibly a breathing tube)
  • Fluids through a vein
  • Laxative
  • Narcotic antagonist (a medicine to reverse the effect of the painkiller)
  • Tube through mouth into the stomach to empty the stomach (gastric lavage)

So, yeap. Good luck with your cough syrups. I strongly discourage OD-ing on this. I don’t think it is safe to share experiences up here for obvious reasons. Just wanna say that it’s really not awesome at all.

I know you are stubborn and you’re still gonna do it.

That’s an intentional pun.

References:

http://www.drugs.com/dextromethorphan.html

http://health.nytimes.com/health/guides/poison/dextromethorphan-overdose/overview.html

http://cold.emedtv.com/dextromethorphan/dextromethorphan-overdose.html

http://www.nhtsa.gov/people/injury/research/job185drugs/dextromethorphan.htm

http://www.healthoma.com/what-can-robitussin-or-dextromethorphan-overdose-do/

http://www.dxmstories.com/dxm_overdose.html

http://www.healthoma.com/what-can-robitussin-or-dextromethorphan-overdose-do/

http://www.erowid.org/chemicals/dxm/dxm_dose.shtml

http://en.wikipedia.org/wiki/Recreational_use_of_dextromethorphan

http://streetroots.wordpress.com/2010/12/22/canada-and-the-u-s-are-making-significant-strides-toward-mainstreaming-harm-reduction-but-there-are-still-walls-to-knock-down/

http://www.emsworld.com/article/10324941/drug-abuse-update-dextromethorphan

 

Disclaimer:

I do not guarantee that everything in this post is accurate because as a 16 y/o that I am, all I did was a brief research (google, command+c, command+v). Any correction would be appreciated. And in case you are any authority that thinks that I’m promoting cough syrup OD please refer to the diagram above and don’t sue me tyvm.

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